RECOVER: Researching COVID to Enhance Recovery

The National Institutes of Health (NIH) created the RECOVER Initiative to learn about the long-term effects of COVID. Help us find answers by sharing your experience and volunteering to participate in research.

Find a study near you

RECOVER seeks to understand, prevent, and treat long-term health effects related to COVID. Researchers call these long-lasting effects PASC (post-acute sequelae of SARS-CoV-2). You may know them as Long COVID.

Learn more about Long COVID

We’re learning by including diverse perspectives.

Including people of all races and ethnicities, genders, ages, and locations in our research helps us understand how Long COVID affects everyone.

Learn more about how RECOVER partners with patients and communities across the US

Millions of people have had COVID-19 — and in many ways, people of color have been hit hardest.

Studies show that people of color are more likely than white people to go to the hospital for health issues related to COVID-19.

American Indian or Alaska Native
3.1xMore likely
Black or African American
2.4xMore likely
Hispanic or Latino
2.3xMore likely
0.8xMore likely
Source: Centers for Disease Control and Prevention

We learn more when we work together.

Groups involved with RECOVER: Health care providers, Researchers, Caregivers, People with PASC or Long COVID, Supporting Organizations, Policymakers.

We learn more when we work together.

Teamwork is at the heart of RECOVER. Researchers, health care professionals, and organizations across the country are working together to find answers. Our studies include many different groups of people — like adults, pregnant people, and children and their caregivers.

Learn how RECOVER research works

More than
500 million
people around the world have had COVID. It’s possible that millions of them could have long-term health effects.

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Recover News and Events

Learn about our latest research, upcoming events, and more.

June 7, 2022Publication
NIH Director’s Blog: Using AI to Advance Understanding of Long COVID Syndrome

One of the most puzzling aspects of the COVID-19 pandemic is understanding why some people who have short-term COVID later develop new symptoms. Or they may continue to have symptoms while also developing new ones. These Long COVID symptoms can vary a lot from person to person, which makes it hard to understand why some people are more likely to have Long COVID. In this blog post, NIH Director Lawrence Tabak, DDS, PhD, discusses an important new RECOVER study published in The Lancet Digital Health that used artificial intelligence computer models to help unravel this mystery.

NIH Director's Blog
May 16, 2022Publication
RECOVER Publication: Scientists use Electronic Health Records and Machine Learning to Better Define Long COVID

In a study published in The Lancet Digital Health, Pfaff and colleagues used electronic health record (EHR) data to find more than 100,000 likely cases of Long COVID in an EHR database of more than 13 million people.

The study findings will help researchers understand the characteristics and risk factors linked to Long COVID diagnosis and will also help identify potential Long COVID patients for clinical trials.
April 27, 2022Research
Research Opportunity Announcement (ROA) for Clinical Trials for the Prevention and/or Treatment of Post-Acute Sequelae of SARS-CoV-2 infection (PASC)

The National Institutes of Health (NIH) is soliciting applications through this ROA for clinical trials in those over 18 years old for the prevention and/or treatment of PASC as part of the NIH RECOVER Initiative. The NIH is seeking proposals for clinical trials testing a range of interventions and using diverse methods to address symptoms/symptom clusters and the underlying mechanisms of the pathobiology of PASC. Trial proposals should reflect community and patient engagement. Funding will utilize NIH’s Other Transaction Authority (OTA). Please direct all inquiries to:

A technical assistance webinar for this ROA was held on Friday, May 6th, 2022.

Watch the Technical Assistance Webinar

Slides from Technical Assistance Webinar (PDF, 1.01 MB)

Summary of FAQs Received by NIH about the Clinical Trials ROA (PDF, 174 KB)
March 28, 2022Protocol
RECOVER Adult Study Protocol Available

The full RECOVER research protocol, or study plan, for adults taking part in RECOVER studies is now available. We are finished planning the adult study protocol, but the protocol may change over time as we learn more. If the protocol is updated, we will share it on the RECOVER website, A version of the protocol in easier to understand language will be available soon.

Explore COVID-19 Resources

Find COVID-19 research information and resources.

CARING for Children with COVID Initiative

Learn about NIH's COVID-19 research priorities with children.

NIH Community Engagement Alliance

Find information to help reach communities hardest hit by the pandemic.

Post-COVID Conditions: Information for Healthcare Providers

Find information to help treat patients.

Connect to Federal Government COVID-19 resources.

CDC's COVID-19 Resources

Access CDC's resources on COVID-19.

Find a COVID-19 vaccination site near you.

Combat COVID

Find clinical trials focused on preventing or treating COVID-19.

Temas de Salud: COVID-19

Find Spanish-language COVID-19 resources.

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